Correlations between Inflammation and Development of Cancer, A Small Review
ثبت نشده
چکیده
Submit Manuscript | http://medcraveonline.com Abbreviations: HIF: Hypoxia Inducing Factor; NLRP: Nucleotide Leucine Rich Protein; ATP: Adenosine Tri Phosphate; TNF α-: Tumor Necrosis Factor Alpha; AKT: Protein Kinase; mTORCMammalian Target of Rapamycin Complex; WNT: Gene Wingless and Protooncogene Integration; MSU: Mono Sodium Urate; PARP: Poly ADP Ribose Polymerase; AIDS: Acquired Immune Deficiency Syndrome; APOBEC: Apolipoprotein B mRNA Editing Enzyme; ROS: Reactive Oxygen Species; PKB: Protein Kinase; NOD: Nucleotide Binding Oligomerization Domain
منابع مشابه
Is There any Possible Association Between Trimethylamine N-Oxide (TMAO) and Cancer? A Review Study
Background: During the transit of digested animal source foods, gut microbiota synthesize metabolites that can affect the body cells. One of these metabolites, i.e. Trimethylamine (TMA) that is an intermediary metabolite, ultimately leads to the production of Trimethylamine N-oxide (TMAO). Several studies have been conducted to show the association between TMAO and different diseases. This arti...
متن کاملInflammation, a Key Factor in Cancer Ambush
Inflammatory condition is the consequence of defensive mechanism of immune system against viral and bacterial infection, tissue injury, UV radiation, stress and etc. Persistently acute inflammation leads to chronic phase which is characterized by production of pro-inflammatory mediators from T cells. These molecules (e.g. IL-6, TNF-&alpha, IL-1&beta and IL-17) are mostly pleiotropic cytokines i...
متن کاملA review of the role of dopamine receptors and novel therapeutic strategies in non-small cell lung cancer (NSCLC)
Lung cancer is a very aggressive and most deadly cancer in both men and women. Lung cancer is divided into two types of small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC). NSCLC is divided into 3 subgroups: adenocarcinoma (AC), squamous cell carcinoma (SqCC) and large cell carcinoma (LCC). Dopamine is involved in controlling motions, cognition, emotions, memory and reward mech...
متن کاملThe Role of Interleukin (IL-22) in immune response to human diseases
Background and aims: IL-22 is an alpha- helical cytokine. IL-22 binds to a heterodimeric cell surface receptor composed of IL-10R2 and IL-22R1subunits. IL-22R is expressed on tissue cells, and it is absent on immune cells. L-22 and IL-10 receptor chains play a role in cellular targeting and signal transduction to selectively initiate and regulate immune responses. The aim of this study was to i...
متن کاملThe Effect of Interval Training on the Expression of Tumor Suppressor Gene, Systemic Inflammation, and Tumor Volume in Breast Cancer–Bearing BALB/c Mice
Introduction: E-cadherin is expressed in most normal epithelial tissues. Loss of E-cadherin can cause dedifferentiation and invasiveness in human carcinomas, leading E-cadherin to be classified as a tumor suppressor. Therefore, the aim of this study was to investigate the effect of interval training on the expression of tumor suppressor gene E-cadherin in breast cancer-bearing BALB/c mice. Meth...
متن کاملThe Role of Inflammation and Changes of Adipose Tissue-Resident Immune Cells in Increasing the Risk of Cancer: A Narrative Review
The incidence of obesity, as a major health problem, has increased significantly over the past decades. This condition is associated with an increased risk of cancers, type 2 diabetes, and cardiovascular diseases. The current study aimed to investigate the effects of inflammation and changes of adipose tissue-resident immune cells on increasing the risk of cancer in obese individuals. In obesit...
متن کامل